The device runs on the Android 11, One UI 3.1 operating system. It features GPS with A-GPS, GLONASS, GALILEO, BDS, and USB Type-C 2.0, USB On-The-Go.

It is fueled with a Li-Po 4500 mAh, non-removable Fast charging 25W, 50% in 30 min (advertised). The smartphone features a 6.5 inches IPS LCD display that has a 1080 x 2400 pixels resolution. The device comes in various colors such as Awesome Black, Awesome White, Awesome Violet, and Awesome Blue.

Samsung Galaxy A52 4G is integrated with a Single SIM (Nano-SIM) or Hybrid Dual SIM (Nano-SIM, dual stand-by). It features quad camera: 64 MP (wide) 12 MP (ultrawide) 5 MP (macro) 5 MP (depth) while on the front there is a 32 MP camera.

The sensors include Fingerprint (side-mounted), accelerometer, gyro, proximity, and compass.